Genomics Services
HER2 (Human Epidermal Growth factor Receptor 2) or ERBB2
Recommended for Breast Cancer

HER2 is a member of the Epidermal Growth Factor Receptor (EGFR) family. ERBB2, a known proto-oncogene is located on long arm of human chromosome 17. HER2 is named because it has a similar structure to human epidermal growth factor receptor. Overexpression of this oncogene plays an important role in the development and progression of certain aggressive types of breast cancer and in some ovarian cancer. HER2 mutation test helps to differentiate between HER2 +/- breast cancer. This protein is an important biomarker and target for therapy selection for approx. 30% of breast cancer patients.

Sample Type

Blood Sample: 5 ml blood in EDTA Vacutainer at 2-8°C
Brochure           inquiry
EGFR (Epidermal Growth Factor Receptor)   |   ALK (Anaplastic lymphoma kinase)
BRAF (B-Raf proto-oncogene, serine/threonine kinase)   |   BRCA1 and BRCA2   |   CHECK2 (Check Point Homolog)
KRAS (Ki-ras2 Kirsten rat sarcoma viral oncogene homolog)   |   Tyrosine Kinase Sensitivity for KIT & PDGFRA
HER2 (Human Epidermal Growth factor Receptor 2) or ERBB2   |   TP53 (Tumor Protein p53)   |   BCR-ABL
Tamoxifen   |   NRAS Mutation   |   Tyrosine Kinase Sensitivity for Abl1 Mutations
HRAS Mutation (Harvey rat sarcoma viral Oncogene Homolog)   |   DPYD Mutation (for 5FU Sensitivity)
MAPK1 Mutation Analysis
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