Genomics Services
EGFR (Epidermal Growth Factor Receptor)
Recommended for Lung Cancer

Epidermal Growth Factor Receptor is a cell surface protein that binds to epidermal growth factor. EGFR gene is located on chromosome 7 at position 12. EGFR mutations are commonly found in exon 18 to 21 of the EGFR gene. Over expression of EGFR gene has been observed in several cancers. More than 60% of the lung cancer cases shows over expression of EGFR, making it an important marker for diagnosis. Early detection is important to understand the pathobiology of lung cancer; tumor biology as well as host responses to first line treatment.

Sample Type

FFPE Tissue: Formalin Fixed Parafin Embedded (FFPE) tissue block with atleast 3-4 sections of tumor tissue. Tissue section should contain >70% tumor content verified by pathologist and should be sent along with 5 H&E stained and 5 unstained slides of tumor tissue.

Fresh Tissue: Fresh tissue in tms RNS stabilizer (XGtms-100) provided by Xcelris Labs in sterile leak proof container at -20°C (in Dry Ice)
Brochure           inquiry
EGFR (Epidermal Growth Factor Receptor)   |   ALK (Anaplastic lymphoma kinase)
BRAF (B-Raf proto-oncogene, serine/threonine kinase)   |   BRCA1 and BRCA2   |   CHECK2 (Check Point Homolog)
KRAS (Ki-ras2 Kirsten rat sarcoma viral oncogene homolog)   |   Tyrosine Kinase Sensitivity for KIT & PDGFRA
HER2 (Human Epidermal Growth factor Receptor 2) or ERBB2   |   TP53 (Tumor Protein p53)   |   BCR-ABL
Tamoxifen   |   NRAS Mutation   |   Tyrosine Kinase Sensitivity for Abl1 Mutations
HRAS Mutation (Harvey rat sarcoma viral Oncogene Homolog)   |   DPYD Mutation (for 5FU Sensitivity)
MAPK1 Mutation Analysis
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